New tetralactam hosts for squaraine dyes
نویسندگان
چکیده
منابع مشابه
New squaraine dyes for photodynamic therapy
Photodynamic therapy (PDT) [1]consists in the activation of molecular oxygen under irradiation by light in the presence of photodrugs (photosensitizers, PS) that have been previously selectively accumulated in the target tissues. In comparison with conventional treatment methods, PDT is considered to be a clinical treatment with high safety, few side effects, reliable repeatability, and relativ...
متن کاملTriptycene-based tetralactam macrocycles: synthesis, structure and complexation with squaraine.
Two novel triptycene-based tetralactam macrocycles as a pair of diastereomers were synthesized, and showed highly efficient complexation with squaraine, which could subsequently protect the squaraine dye from polar solvents.
متن کاملSinglet oxygen generation using iodinated squaraine and squaraine-rotaxane dyes.
The goal of this study was to assess the ability of squaraine-rotaxanes to generate singlet oxygen for potential application in photodynamic therapy (PDT). Specifically, we compare the aggregation and photophysical properties of an iodinated squaraine dye and an iodinated squaraine-rotaxane. Even under strongly aggregating conditions, the absorption spectra of both remain relatively sharp. An X...
متن کاملSquaraine-derived rotaxanes: highly stable, fluorescent near-IR dyes.
Squaraines are fluorescent, near-IR dyes with promising photophysical properties for biomedical applications. A limitation with these dyes is their inherent reactivity with nucleophiles, which leads to loss of the chromophore. Another drawback is their tendency to form nonfluorescent aggregates in water. Both problems can be greatly attenuated by encapsulating the dye inside an amide-containing...
متن کاملSquaraine-derived rotaxanes: sterically protected fluorescent near-IR dyes.
A squaraine dye with bulky end groups is employed as the thread component in two Leigh-type amide rotaxanes. The rotaxanes are synthesized in a simple two-step process. X-ray crystal structures of the rotaxanes show that the pyridyl-containing macrocycle is more rigid and wraps more tightly around the cyclobutene core of the squaraine thread compared to the isophthalamide-containing macrocycle....
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2018
ISSN: 1477-0520,1477-0539
DOI: 10.1039/c8ob02596g